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Fig. 3 | BMC Genomics

Fig. 3

From: Transcriptome analysis reveals differences in mechanisms regulating cessation of luteal function in pregnant and non-pregnant dogs

Fig. 3

Venn diagram showing the intersection of differentially expressed genes (DEG) in the contrast “luteal regression over luteolysis” compared with the contrast “mid-gestation over antigestagen”. Lists of DEG (p < 0.01, FDR < 0.1) presented in Additional files 1 and 3 were used. Three analyses are presented: with up- and down-regulated genes (regardless of log2 ratio), or with upregulated genes (log2 > 1), or with downregulated genes (log2 < −1). When full sets of genes were used (up and down regulated), 11 genes were found overlapping in both contrasts, 1584 genes were found only in the contrast “luteal regression over luteolysis” and 81 genes were found in “mid-gestation over antigestagen”. Adding log2 ratio > 1 to the threshold, 2 over-represented genes overlapped in both contrasts, and for log2 ratio < −1, 5 downregulated genes were found

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