Table 4 Histone modification patterns (obtained from HHMD) of novel hub genes with respect to the already known histone modification sites in neurodegenerative diseases
Novel hub genes | Official symbol | RefSeq ID | Histone modification sites already known in neurodegenerative diseases | ||||
|---|---|---|---|---|---|---|---|
H3K27 | H3K4 | H3K9 | H3K9/H4K20 | H4R3 | |||
MAGED1 | MAGED1 | NM_006986 | √ | √ | √ | √ | √ |
AP3B2 | AP3B2 | NM_004644 | √ | √ | √ | √ | √ |
STXBP1 | STXBP1 | NM_001032221 | √ | √ | √ | √ | √ |
AF1Q | MLLT11 | NM_006818 | √ | √ | √ | √ | √ |
GASP | GPRASP1 | √ | √ | √ | √ | √ | |
C14ORF78 | AHNAK2 | NM_138420 | √ | √ | √ | √ | √ |
MAN1C1 | MAN1C1 | NM_020379 | √ | √ | √ | √ | √ |
HNRPC | HNRNPC | √ | √ | √ | √ | √ | |