Fig. 2

Statistics of total differentially expressed genes. a Numbers of total differentially expressed genes between adjacent samples. The numbers of up-regulated and down-regulated genes are represented in red and blue, respectively. The graphics at the top show the main changes of cell types and structure of follicles during the oogenesis, which is the abstract rendering of the microstructures in Fig.1A. The outer cells represent the follicle epithelial cells. The yellow parts represent the oocyte and the nurse cells. The blue circles represent the nuclei of follicle epithelial cells and oocytes. The brown and red lines represent the vitelline membrane and chorion layer. b Enrichment map for significantly enriched GO terms. The level of overlap between GO enriched terms is indicated by the thickness of the edge between them. The size of the node indicates the size for the term, and the gene group for which the term was found to be significant (FDR < 0.05, Overlap coefficient cut-off >0.25); the color of the node indicates the absolute value of the base 10 logarithm of the FDR. c Enrichment map for significantly enriched KEGG pathways