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Table 1 The main and epistatic effect miRNAs identified to be associated with pathological stages of colon cancer in our study

From: Epistasis analysis of microRNAs on pathological stages in colon cancer based on an Empirical Bayesian Elastic Net method

Effect-type miRNAs β
Main Effect hsa-let-7c −0.0321
hsa-mir-1249 −0.0668
hsa-mir-31 0.0466
hsa-mir-3189 −0.0475
hsa-mir-320c-1 −0.0535
hsa-mir-337 −0.0633
hsa-mir-34a −0.0382
hsa-mir-3662 −0.0630
hsa-mir-548e −0.0404
hsa-mir-580 0.0400
hsa-mir-3065 0.0512
Epistatic Effect hsa-let-7d, hsa-mir-548v −0.0077
hsa-mir-1254, hsa-mir-3615 0.0559
hsa-mir-223, hsa-mir-3913-1 −0.0126
hsa-mir-296, hsa-mir-432 0.0073
hsa-mir-3131, hsa-mir-874 0.0078
hsa-mir-3150b, hsa-mir-3610 0.0512
hsa-mir-363, hsa-mir-937 0.0090
hsa-mir-3682, hsa-mir-483 0.0020
hsa-mir-3917, hsa-mir-3928 −0.0462
hsa-mir-433, hsa-mir-616 −0.0383
hsa-mir-496, hsa-mir-937 0.0143
hsa-mir-511-1, hsa-mir-7-2 0.0069
hsa-mir-3065, hsa-mir-656 0.0284
hsa-mir-577, hsa-mir-92b −0.0189
  1. The effect-type describes either main or epistatic effect. miRNAs denote either individual miRNAs with main effect or miRNA pairs with epistatic effect. β values describe the effect sizes of selected miRNAs or miRNA pairs, learned from the model