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Table 1 The main and epistatic effect miRNAs identified to be associated with pathological stages of colon cancer in our study

From: Epistasis analysis of microRNAs on pathological stages in colon cancer based on anĀ Empirical Bayesian Elastic Net method

Effect-type

miRNAs

Ī²

Main Effect

hsa-let-7c

āˆ’0.0321

hsa-mir-1249

āˆ’0.0668

hsa-mir-31

0.0466

hsa-mir-3189

āˆ’0.0475

hsa-mir-320c-1

āˆ’0.0535

hsa-mir-337

āˆ’0.0633

hsa-mir-34a

āˆ’0.0382

hsa-mir-3662

āˆ’0.0630

hsa-mir-548e

āˆ’0.0404

hsa-mir-580

0.0400

hsa-mir-3065

0.0512

Epistatic Effect

hsa-let-7d, hsa-mir-548v

āˆ’0.0077

hsa-mir-1254, hsa-mir-3615

0.0559

hsa-mir-223, hsa-mir-3913-1

āˆ’0.0126

hsa-mir-296, hsa-mir-432

0.0073

hsa-mir-3131, hsa-mir-874

0.0078

hsa-mir-3150b, hsa-mir-3610

0.0512

hsa-mir-363, hsa-mir-937

0.0090

hsa-mir-3682, hsa-mir-483

0.0020

hsa-mir-3917, hsa-mir-3928

āˆ’0.0462

hsa-mir-433, hsa-mir-616

āˆ’0.0383

hsa-mir-496, hsa-mir-937

0.0143

hsa-mir-511-1, hsa-mir-7-2

0.0069

hsa-mir-3065, hsa-mir-656

0.0284

hsa-mir-577, hsa-mir-92b

āˆ’0.0189

  1. The effect-type describes either main or epistatic effect. miRNAs denote either individual miRNAs with main effect or miRNA pairs with epistatic effect. Ī² values describe the effect sizes of selected miRNAs or miRNA pairs, learned from the model
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BMC Genomics

ISSN: 1471-2164

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