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Table 3 Summary of target genes associated with colon cancer according to OMIM database

From: Epistasis analysis of microRNAs on pathological stages in colon cancer based on an Empirical Bayesian Elastic Net method

Location Phenotype miRNA ID Target genes
1p13.2 Colon cancer, somatic hsa-let-7c, hsa-let-7d, hsa-mir-363, NRAS
hsa-mir-3913, hsa-mir-483, hsa-mir-874
3q26.32 Colon cancer, somatic hsa-mir-363 PIK3CA
4p16.3 Colon cancer, somatic hsa-mir-296, hsa-mir-337, hsa-mir-874 FGFR3
5q22.2 Colon cancer, somatic hsa-mir-22, hsa-mir-3065, hsa-mir-497, hsa-mir-7-2 APC
5q22.2 Colon cancer, somatic hsa-mir-1249, hsa-mir-3662, hsa-mir-548e MCC
hsa-mir-548v, hsa-mir-7-2
7q11.23 Colon cancer, somatic hsa-mir-874 PTPN12
11p11.2 Colon cancer, somatic hsa-mir-363, hsa-mir-497 PTPRJ
11q13.3 Colon cancer, susceptibility to hsa-mir-432, hsa-mir-497, hsa-mir-511 CCND1
14q24.3 Colorectal cancer, somatic hsa-mir-432 MLH3
14q32.33 Colorectal cancer, somatic hsa-mir-1249, hsa-mir-548e, hsa-mir-656 AKT1
17p13.1 Colon cancer hsa-mir-1249 TP53
17q24.1 Colorectal cancer, somatic hsa-mir-1249, hsa-mir-497, hsa-mir-616 AXIN2
18q21.2 Colorectal cancer, somatic hsa-mir-363, hsa-mir-3662, hsa-mir-3913, hsa-mir-548e DCC
20q13.2 Colon cancer, susceptibility to hsa-mir-363 AURKA
22q13.2 Colorectal cancer, somatic hsa-let-7c, hsa-mir-497 EP300