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Table 1 Patient sample nomenclature and viral copy number

From: Single-virion sequencing of lamivudine-treated HBV populations reveal population evolution dynamics and demographic history

Sample ID Patient Date Viral Copies/ul Single-virion Sequences Nucleotide Diversity ∏
1.1 1 15th Nov 94 378,500 1717, 1635* 0.0012/base
1.2 1 3rd Jul 99 52,270 3331, 2514* 0.0024/base
2.1 2 22nd May 95 239,750 391, 1330* 0.0032/base
2.2 2 29th Aug 97 44,687 3747, 2504* 0.0013/base
7.1 7 19th May 95 69,180 2647 0.0022/base
7.2 7 11th Apr 00 48,083 789 0.0016/base
11.1 11 19th Jun 95 208,275 2754 0.0211/base
11.2 11 3rd Nov 98 466,200 248 0.0052/base
  1. -total number of single-virion sequences obtained from a BAsE-Seq library. *-total number of single-virion sequences obtained from a PacBio library. Nucleotide diversity Π, the arithmetic mean between all pairwise differences between viral sequences within each viral population, were calculated from BAsE-Seq single-virion sequences for the entire amplified genomic sequence of 3175 bases (3215 minus the 40 bases that were not amplified)