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Table 1 Baseline characteristics of eligible participants in the different cohorts

From: Genetic determinants of growth hormone and GH-related phenotypes

  MDC-CC - Discovery MPP - Replication MDC - Anthropometry
Number of participants 4134 5262 24,047
Female (%) 2405 (58.2) 1522 (28.9)*** 14,588 (60.7)**
Age, mean (SD), years 57.7 (6.0) 69.3 (6.3)*** 58.1 (7.9)**
Body Mass Index, mean (SD), kg/m2 25.8 (3.9) 27.2 (4.2)*** 25.8 (4.1)
Waist, mean (SD), cm 83.8 (12.9) 95.8 (12.2)*** 84.5 (13.1)**
Waist-hip-ratio (SD) 0.85 (0.09) 0.93 (0.09)*** 0.85 (0.09)
Bodyfat percentage, mean (SD), % 27.6 (7.1) N/A 26.8 (7.0)***
Height, mean (SD), cm 169 (9) 171 (9)*** 169 (9)
Diabetes Mellitus (%) 367 (8.9) 615 (11.7)*** 1043 (4.3)***
Smoking (%) 1081 (26.1) 1028 (19.5)*** 6338 (26.4)
Lipid-lowering therapy (%) 89 (2.2) 1060 (20.1)*** 762 (3.2)***
Growth Hormone - males, median (IQR), μg/L 0.11 (0.06–0.33) 0.40 (0.11–1.27)*** N/A
Growth Hormone - females, median (IQR), μg/L 1.21 (0.38–3.12) 0.49 (0.14–1.62)*** N/A
  1. *p < 0.05 for difference compared with MDC-CC. **p < 0.01 for difference compared with MDC-CC. ***p < 0.001 for difference compared with MDC-CC