Genetic determinants of growth hormone and GH-related phenotypes

BMC Genomics

Table 4 Nominally significant SNPs in GHR-gene in MDC-CC

SNP	Basepair^a	Major allele	Minor allele	MAF	Beta	95%CI	P
rs13188386	42,473,555	G	A	0.26	0.085	0.018 to 0.151	0.01
rs13153388	42,507,333	T	G	0.44	0.088	0.029 to 0.147	0.003
rs4365846	42,547,255	A	G	0.24	0.087	0.018 to 0.156	0.01
rs6883523	42,564,748	G	T	0.18	0.079	0.003 to 0.155	0.04

Minor allele modeled as effect allele.The β coefficients are expressed as the increment of standardized values of the natural logarithm of hs-GH per 1 minor allele. Adjusted for age and sex
Abbreviations: MAF Minor allele frequency.Number of individuals available for analysis: 4126–4131
^aBasepair number for polymorphism (GRCh37). All the SNPs are located in the GHR-gene on chromosome 5

ISSN: 1471-2164