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Table 2 Dynamic programming illustration. i: the subscript of the table; d: the DNA sequence; r: the sgRNA sequence; H: the number of base mismatches; L1: 1-base DNA bulge; R1: 1-base RNA bulge; L2: 2-base DNA bulge; R2: 2-base RNA bulge

From: Whole genome analysis of CRISPR Cas9 sgRNA off-target homologies via an efficient computational algorithm

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BMC Genomics

ISSN: 1471-2164

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