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Table 2 Details of the regions of difference (RD) of lengths greater than 500 bp in the sequenced strains from Uruguay, as well as deletions found in PE/PPE-coding genes. Each RD is defined by an ID, and all deletions show the number of ORFs that cover, starting and ending coordinates, length, strains presenting these deletions and spoligotypes associated with them. Marked in bold are the RDs with more robust association to a given spoligotype

From: Whole genome sequencing of the monomorphic pathogen Mycobacterium bovis reveals local differentiation of cattle clinical isolates

ID

Genes covered

Start

End

Length

Strains (MbURU-)

Spoligotypes associated

Previously described

RD3

14, Mb 1598-Mb1611c

1,764,652

1,773,872

9221

001, 002, 003, 005, 007, 0010, 012, 014, 016

SB0145, SB0130

 

RDbov145a

2, Mb0026-Mb0027

29,475

30,078

604

001, 003, 005, 014, 016, 019, 020

SBO145

 

RDbovI 31

5, Mb0677c-Mb0681c

756,105

757,654

1550

010

X

 

RDbov145b

1, serA2

824,054

824,599

546

001, 003, 005, 014, 016, 019, 020

SB0145

 

RDbov145c

2, Mb0930-Mb0931

1,009,480

1,010,927

1448

001, 003, 005, 014, 016, 019, 020

SB0145

 

RDbovI 072

7, Mb1908-Mb1914c

2,116,213

2,122,816

6604

006

SB1072

 

RDbovI 32

1, rmlB2

3,832,661

3,833,913

1253

007

X

 

RDbov133

2, bisC-Mb1478c

1,616,260

1,619,455

3196

012

X

 

RDbov134

1, Mb3756

4,115,825

4,116,744

920

012

X

 

RDbov130a

1, Mb3923c

4,310,701

4,311,694

994

002, 007, 010, 012, 017, 018

SB0130

PE/PPE

1, PE_PGRS19

1,189,852

1,190,034

183

001, 003, 005, 014, 016, 019, 020

SB0145

1, PE_PGRS20

1,192,321

1,192,742

422

001, 003, 005, 014, 016, 019, 020

SB0145

1, PE_PGRS24

1,486,342

1,486,528

187

001, 003, 005, 014, 016, 019, 020

SB0145

1, PPE30

2,033,505

2,033,624

120

002, 007, 010, 012, 017, 018

SB0130

1, PE_PGRS42d

2,762,816

2,762,980

165

004, 008, 009, 011, 013, 015, 021, 022, 023

SB0140, SB0274

1, PE_PGRS50b

3,691,479

3,691,697

219

004, 006, 008, 009, 011, 013, 015, 021, 022, 023

SB0140, SB0274, SB1072

1, PE_PGRS50b

3,694,231

3,694,311

81

006

SB1072

1, PE_PGRS51

3,733,072

3,733,247

176

001, 003, 005, 014, 016, 019, 020

SB1045