Table 1 Pairwise comparisons of single nucleotide variant (SNV) counts for Vibrio cholerae clinical and water isolates by WGS
|  | Pairwise Comparisons* | All Outbreaks | p-value†|
|---|---|---|---|
Mean SNV ± SD (Min-Max) | |||
Inter vs. Intra Household Variability in SNV Counts | |||
 Isolates from Same Households | 33 | 2.4 ± 3.1 (0–12) | <0.0001 |
 Isolates from Different Households | 670 | 7.7 ± 4.8 (1–21) |  |
Same MLVA Genotype vs. Different MLVA Genotype Variability in SNV Counts | |||
 Same MLVA Genotype | 77 | 4.8 ± 4.9 (0–18) | <0.0001 |
 Different MLVA Genotype | 628 | 7.7 ± 4.8 (0–21) |  |
Single Locus Variants in MLVA Genotype vs. Different MLVA Genotype Variability in SNV Counts | |||
 Single Locus Variants in MLVA Genotypes | 89 | 4.7 ± 3.1 (0–15) | <0.0001 |
 Different MLVA Genotype | 539 | 8.2 ± 4.8 (1–21) |  |
Clinical vs. Water Isolate Variability in SNV Counts | |||
 Clinical Isolates | 231 | 6.2 ± 3.7 (1–18) | <0.0001 |
 Water Isolates | 120 | 9.0 ± 6.1 (1–20) |  |
Same vs. Different Outbreaks Variability in SNV Counts | |||
 Isolates from Same Outbreak | 232 | 6.1 ± 4.9 (0–21) | 0.01 |
 Isolates from Different Outbreak | 473 | 8.0 ± 4.8 (1–21) |  |