Effect of short term diet restriction on gene expression in the bovine hypothalamus using next generation RNA sequencing technology

Table 4 Enriched genetic pathways between Restricted Ovulatory and Control groups from Innatedb

Pathway name	Genes	Total no. of genes in pathway	P value
Apoptotic cleavage of cell adhesion proteins	CADH1 ↓, DSP ↓	11	7.81E-05
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	CADH1 ↓, Q05B55 ↓,	74	0.001265006
Apoptotic cleavage of cellular proteins	CADH1 ↓, DSP ↓	36	0.001499709
Arf6 trafficking events	CADH1 ↓, TSHR ↓	39	0.001743312
Apoptotic execution phase	CADH1 ↓, DSP ↓	42	0.001980774
Proteinase-activated receptor G (12/13) cascade	PAR1 ↓	3	0.003148078
Thrombin-mediated activation of PARs	PAR1 ↓	4	0.004671547
Platelet Activation	PAR1 ↓, TSP4 ↓	95	0.005884444
Signaling by GPCR	PAR1 ↓, TSHR ↓	648	0.006837614
Classical antibody-mediated complement activation	Q05B55 ↓	24	0.007641167
Proteinase-activated receptor G (q) cascade	PAR1 ↓	6	0.007793549
Thrombin signalling G-protein cascades	PAR1 ↓	6	0.007793549
Sumoylation as a mechanism to modulate ctbp-dependent gene responses	CADH1 ↓	8	0.008891268
Formation of Platelet plug	PAR1 ↓, TSP4 ↓	114	0.00923053
Thrombin signalling through PARs	PAR1 ↓	7	0.009310227

Expression is Restricted Ovulatory relative to Control. eg. CADH1 ↓ means RO has decreased expression of this compared to C

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