A novel algorithm for finding optimal driver nodes to target control complex networks and its applications for drug targets identification

Table 4 The properties of detected driver nodes with Liu’s method, Gao’s method, and our method in Pancreatic cancer network

Method	Pancreatic cancer network		Inflammatory bowel disease network
Method	f1	f2	f1	f2
Liu [6]	4.0952	0.0596	39.0208	0.0806
Gao [8]	0.8750	0.0748	0.7917	0.1316
Our method	0.4702	0.4302	0.1875	0.5506

The columns represent the following information per disease network: Different methods, the fraction of the quantity of drivers vs. the target nodes (f1), the fraction of the driver nodes within drug target nodes in FDA vs. the quantity of driver nodes (f2)

ISSN: 1471-2164