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Fig. 1 | BMC Genomics

Fig. 1

From: Discovery of cell-type specific DNA motif grammar in cis-regulatory elements using random Forest

Fig. 1

Our bioinformatics workflow for DNA motif annotation, Random Forest (RF) classifier training and motif grammar extraction. The workflow consists of four steps. a Step 1: extraction of the genomic sequences from the cell-type specific TF binding sites. b Step 2: annotation of these sequences using a large database of motifs. c Step 3: training of a RF classifier. d Step 4: Motif rule (grammar) extraction from the RF classifier

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