Fig. 4

Circular representations of C. difficile chromosomes generated with BRIG software. From the outside: circle 1 shows identified mobile elements (black – prophages P1–7, pink – conjugative transposons CT). Circle 2 shows reference genome a strain DSM 27638 / DSM 27640, b strain DSM 27639). The most inner circle represents scale (in kb), second inner – GC skew for reference genome, third – GC content graph. Inner rings represent analyzed genome sequences of red colors ribotype 027 (the most dark red: DSM 27638 then 2,007,855, R20291, and light red 196); blue colors represent 012 ribotype (dark blue: 630, light blue: DSM 27639); green colors represent ribotype 017 (dark green: CF5, light green: M68) and yellow color represent strain M120 belonging to RT 078