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Table 1 Antibiotic resistance patterns of the three C. difficile strains

From: Comparative genome and phenotypic analysis of three Clostridioides difficile strains isolated from a single patient provide insight into multiple infection of C. difficile

Isolate

Rifampicin

bVancomycin

bMetronidazole

cMoxifloxacin

Erythromycin

DSM 27638

a0.004

S (0.5)

S (0.38)

R (>32)

R (>256)

DSM 27639

S (0.003)

S (0.75)

S (0.25)

S (2)

R (>256)

DSM 27640

a0.004

S (0.38)

S (0.25)

R (>32)

R (>256)

DSM 27543

S (0.003)

S (0.5)

S (0.25)

S (2)

R (>256)

DSM 27147

a0.004

S (0.5)

S (0.38)

R (>32)

R (>256)

  1. May be tested for epidemiological purposes only (ECOFF 4 mg/L (EUCAST Clinical Breakpoint Table v. 7.1.). DSM 27543 (630) and DSM 27147 (R20291) served as controls
  2. MIC given in mg/mL, S sensitive, R resistant
  3. aNot used clinically. May be tested for epidemiological purposes only (ECOFF 0.004 mg/L). Vancomycin: R > 2 mg/L. Metronidazole: R > 2
  4. bThe breakpoints are based on epidemiological cut-off values, which distinguish wild-type isolates from those with reduced susceptibility
  5. cNot used clinically