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Fig. 7 | BMC Genomics

Fig. 7

From: A prototypical non-malignant epithelial model to study genome dynamics and concurrently monitor micro-RNAs and proteins in situ during oncogene-induced senescence

Fig. 7

MiR analysis of HBEC CDC6 Tet-ON cellular system. a Principal component analysis of miR profiles showing that after escaping from the senescence programme, the cells reverted to the pre-induction stage, but considerable alterations of their miR expression persisted. b Hierarchical clustering of miRs that showed significant differences between the non-induced (OFF), induced (3d On and 6d On) and escaped from senescence (Escaped) cells

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