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Table 2 Mean (SD) 1500 m, 3000 m, 5000 m, 10,000 m and marathon best running times in (a) males and (b) females in the three ACE I/D genotypes

From: No association between ACTN3 R577X and ACE I/D polymorphisms and endurance running times in 698 Caucasian athletes

(a)

ACE I/D males

DD

N = 314

32.4%

ID

N = 452

46.6%

II

N = 204

21.0%

Additive

(DD = 0, ID = 1, II = 2)

Recessive

(DD = ID = 0, II = 1)

 Running time 1500 m (s)

233.3 (16.4)

29.9%

235.1 (11.6)

45.8%

235.7 (13.1)

24.3%

p = 0.50

p = 0.67

 Running time 3000 m (s)

519.5 (28.0)

34.7%

517.7 (29.4)

43.7%

518.1 (24.7)

21.6%

p = 0.77

p = 0.93

 Running time 5000 m (s)

914.1 (62.9)

31.7%

918.9 (60.8)

48.0%

916.1 (53.4)

20.3%

p = 0.80

p = 0.93

 Running time 10,000 m (s)

1882.6 (101.3)

32.4%

1894.1 (116.6)

47.5%

1908.0 (132.1)

20.1%

p = 0.36

p = 0.45

 Running time marathon (s)

9181.8 (665.1)

32.4%

9213.7 (549.0)

47.0%

9155.3 (491.5)

20.6%

p = 0.85

p = 0.57

(b)

ACE I/D females

DD

N = 127

28.4%

ID                 N = 229

51.2%

II

N = 91

20.4%

Additive

(DD = 0, ID = 1, II = 2)

Recessive

(DD = ID = 0, II = 1)

 Running time 1500 m (s)

268.7 (11.8)

37.5%

271.1 (18.8)

45.8%

263.9 (14.5)

16.7%

p = 0.65

p = 0.32

 Running time 3000 m (s)

595.1 (31.2)

27.0%

612.9 (41.2)

53.9%

617.9 (40.2)

19.1%

p = 0.05

p = 0.30

 Running time 5000 m (s)

1062.1 (65.0)

26.0%

1057.2 (103.0)

50.6%

1052.9 (95.9)

23.4%

p = 0.76

p = 0.81

 Running time 10,000 m (s)

2140.8 (112.6)

30.6%

2090.4 (170.3)

52.8%

2095.1 (184.6)

16.7%

p = 0.48

p = 0.85

 Running time marathon (s)

10,604.3 (560.9)

27.4%

10,765.9 (740.0)

51.3%

10,771.1 (707.8)

21.3%

p = 0.21

p = 0.61

  1. All running times are expressed in seconds because statistical analyses were performed on times converted to seconds. The last two columns of the table correspond to the p-value of the linear regression, using an additive or a recessive genetic model. The percentage values represent the genotype proportions