Fig. 3

Displaying mutation landscapes by CoMut plot. In-house script is used to render significantly altered genes and their relevant mutation events into heat maps and bar graphs, which are aligned and interconnected via a common X- or Y-axes, particularly suitable for presenting data with intricate and associative natures. The OncoPrint sorting method is also adapted to display genomic alterations in the gene sets of specific signaling pathways in a mutually exclusive manner and to identify driver mutations in cancers