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Fig. 6 | BMC Genomics

Fig. 6

From: Transcription start site profiling uncovers divergent transcription and enhancer-associated RNAs in Drosophila melanogaster

Fig. 6

Novel unannotated TSSs (nuTSS) cluster into functional categories. a Clusters of nuTSSs based on enrichment of H3K4me1 (red), H3K4me3 (green), H3K27ac (teal), and H3K36me3 (purple). The number of nuTSSs in each cluster is indicated at the right of the plot. b ATAC-seq signal at obsTSSs (dark blue) and nuTSSs from different histone PTM-based clusters. c Nuclear RNA-seq reads were mapped to regions 200 nt upstream and downstream of each TSS, and enrichment of downstream vs. upstream reads was analyzed as a proxy for elongation. At right: boxplot of –Log10-transformed adjusted p-values for downstream signal enrichment over upstream within each nuTSS cluster (downstream-enriched nuTSSs above zero, upstream-enriched nuTSSs below zero)

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