Fig. 2

Chromatin states signatures for breast cancer subtypes. a Genome wide subtype specific patterns revealed by chromatin state clustering (chromatin state color scheme same as Fig. 1b). The Heatmap represents the top 1000 highly variable genomic regions clustered according to average linkage distance metric. b Pie chart of major chromatin states categories in subtype specific patterns across all cell lines. c Genebody H3K36me3 occupancy heatmap for genes associated with active transcription states. d Promoter H3K27me3 occupancy heatmap for genes associated with repressive states