Genome-wide transcriptional analyses in Anopheles mosquitoes reveal an unexpected association between salivary gland gene expression and insecticide resistance

Table 2 Whole-genome microarray studies in which D7 expression was associated with insecticide resistance

Mosquito Species	Country of collection	Insecticide	D7 gene	Reference
An. funestus	Malawi	Bendiocarb, Permethrin	D7r1, D7r2^a, D7r3^b	[48]
An. funestus	Mozambique, Malawi	Permethrin	D7r4	[49]
An. funestus	Zambia	Deltamethrin	D7r1	[18]
An. funestus	Zambia	Etofenprox, Lambda-cyhalothrin	D7r2, long form D7^c	[18]
An. funestus	Senegal	Lambda-cyhalothrin	D7r1	[49]
An. coluzzi	Burkina Faso, Cote d’Ivoire	Deltamethrin	D7L2	[19]
An. gambiae s.s.	Zambia	Deltamethrin	D7r1, D7r2, D7r3, D7r5, D7L2	[18]
An. arabiensis	Sudan	Permethrin	D7r2, D7r4	[50]
An. arabiensis	Uganda	Permethrin	D7r2, D7r4, D7L1	[20]
An. arabiensis	Zanzibar	Lambda-cyhalothrin	D7r4	[51]

^aD7r2 overexpressed in bendiocarb-resistant vs. unexposed control, overexpressed in pyrethroid-resistant vs. unexposed control, and underexpressed in unexposed control vs. susceptible colony
^bD7r3 overexpressed in bendiocarb-resistant vs. unexposed control, underexpressed in unexposed control vs. susceptible colony
^cD7r2 and long form D7 underexpressed in resistant vs. susceptible colony

ISSN: 1471-2164