Fig. 4

The trichothecene biosynthetic gene clusters within F. venenatum, F. graminearum, F. sporotrichioides and F. langsethiae. Presented is the presence (blue) or absence/loss of function (orange) TRI genes within the respective Fusaria, in addition to the conservation of the flanking genes beyond the TRI clusters (grey). 5′ gene key: A. Haloacid dehydrogenase, B. Glycosyl hydrolase family 115, C. Glycoside hydrolase family 17, D. SGNH hydrolase-type esterase, E. Tyrosinase, M. Membrane protein, N. Gal4-like transcription factor, P. Sugar transporter, R. Glycoside hydrolase, family 29, S. Acyl-CoA N-acyltransferase, T. Phosphate permease, U. Unknown, ZC. Signal transduction histidine kinase, ZD. Isoprenylcysteine carboxyl methyltransferase. 3′ gene key: F. NodB-like polysaccharide deacetylase, G. Unknown, H. Signal peptide containing protein, I. 3-hydroxyacyl-CoA dehydrogenase, J. NADH:cytochrome b5 reductase, K. Unknown, L. Cytochrome P450, E-class, group IV, O. Unknown, Q. WW domain-containing oxidoreductase, V. CTP synthase, W. ATP-citrate lyase/succinyl-CoA ligase, X. Acetyl-CoA synthetase-like, Y. Acyl-CoA N-acyltransferase (siderophore biosynthesis protein), Z. ABC transporter type 1, ZA. Major facilitator transporter, ZB. Major facilitator transporter, ZE. Beta-lactamase/transpeptidase-like, ZF. Peptidase C45, ZG. Thiamin pyrophosphokinase, ZH. Unknown