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Table 1 Significant CNV from genome-wide association analysis for RFI and DMI traits among Holstein cattle

From: Genome-wide copy number variant analysis reveals variants associated with 10 diverse production traits in Holstein cattle

Ā Ā Ā Ā 

P-value after FDR correction

Overlapped Ensemble

Ā Ā 

CNV

Chromosome

Start (bp)

End (bp)

DMI

RFI

Gene ID

Gene Symbol

Overlapped QTL

CNV1

4

108,225,979

108,252,635

0.0012

0.0000

Ā 

LOC787786 (OR2A2)

Ā 

CNV25

16

79,851,676

79,853,884

0.2802

0.0236

Ā Ā Ā 

CNV28

16

78,028,784

78,035,505

0.9670

0.0367

ENSBTAG00000002291

ZBTB41

Ā 

CNV31

8

44,934,828

44,944,671

0.3442

0.0201

Ā 

LOC101909075

Ā 

CNV32

3

14,876,353

14,882,132

0.1561

0.0259

ENSBTAG00000046885

RXFP4

Ā 

CNV38

11

93,188,055

93,190,178

0.6321

0.0391

Ā Ā 

Stearic acid content

CNV43

5

9,756,491

9,757,695

0.4402

0.0027

Ā Ā 

Infectious bovine keratoconjunctivitis susceptibility, Cold tolerance, Calving ease (maternal), Male fertility, Gestation length, Milk alpha-lactalbumin %, Retained placenta (DYD), Milk protein %

CNV66

7

42,745,346

42,788,788

0.4395

0.0274

ENSBTAG00000046318

LOC787816 (OR2T12)

Cold tolerance

Ā Ā Ā Ā Ā Ā 

ENSBTAG00000007557

OR2AK2

Average daily gain

CNV84

1

143,922,352

143,945,292

0.7750

0.0357

Ā Ā Ā 

CNV120

14

44,862,013

44,868,983

0.3398

0.0025

Ā Ā 

Subcutaneous fat

  1. Note: See Additional file 2: Table S4 for additional details. P-values <ā€‰0.05 are indicated in bold font