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Table 2 Results of the gene enrichment analysis

From: Additional oxidative stress reroutes the global response of Aspergillus fumigatus to iron depletion

Comparison Up- Down- Significant enriched FunCat termsa
regulated genes for up regulated genes for down regulated genes
-Fe/-H2O2 vs. +Fe/-H2O2 1107 1383 secondary metabolism, drug/toxin transport, homeostasis of metal ions, siderophore-iron transport, degradation of aspartate translation, Fe/S binding, ribosome biogenesis, secondary metabolism, aerobic respiration, detoxification involving cytochrome P450, heme binding, TCA pathway, metabolism of melanins, catalase reaction
+Fe/+H2O2 vs. +Fe/-H2O2 347 339 secondary metabolism secondary metabolism, siderophore-iron transport, extracellular polysaccharide degradation, homeostasis of metal ions
-Fe/+H2O2 vs. -Fe/-H2O2 2125 2028 proteasomal degradation, heat shock response, vacuolar/lysosomal transport, oxidative stress response, DNA repair ribosome biogenesis, translation, allantoin and allantoate transport, secondary metabolism, vitamin/cofactor transport, fatty acid metabolism, virulence and disease factors, degradation of glutamine
-Fe/+H2O2 vs. +Fe/-H2O2 2420 2344 vacuolar/lysosomal transport, heat shock response, proteasomal degradation, transcription initiation, vacuole or lysosome, DNA repair ribosome biogenesis, translation, Fe/S binding, TCA pathway, secondary metabolism, aerobic respiration, detoxification involving cytochrome P450, allantoin and allantoate transport, disease-virulence-defense, heme binding
  1. aSelected significant (p < 0.05) shared FunCat terms are presented. The full data sets, which also contain the significant shared GO and KEGG pathway terms are available in Additional file 2