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Fig. 3 | BMC Genomics

Fig. 3

From: Waveband specific transcriptional control of select genetic pathways in vertebrate skin (Xiphophorus maculatus)

Fig. 3

X. maculatus exposed to 35 kJ/m2 FL differentially modulated 413 genes which were analyzed using IPA (Qiagen). 391 genes (95% of the overall response) were able to be categorized into 74 statistically significant functional classes (z-score ± 2; 5 gene minimum); the remaining 5% of the genes modulated either failed to fall into a statistically significant functional class or could not be properly annotated and mapped by IPA. The 74 functional classes represent 10 primary categories; cell cycle; cellular assembly/organization; cellular movement; cellular growth/proliferation; DNA replication, recombination/repair; organismal survival; tissue development; organismal injury/abnormality; immunological disease; and cell death and survival. The 19 functional classes shared between FL and the 50 or 10 nm wavebands are shown by color highlighting the gene number. Compensatory effects due to the combined exposure by multiple wavebands is assumed to be responsible for the remaining 55 functional classes observed following FL exposure. For complete gene lists of each functional class see Additional file 2: Table S2a

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