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Table 1 Summary of potential ligand-receptor interactions in cumulus-oocyte complexes and corresponding genes expressed in oocytes and cumulus cells annotated

From: Functional signaling and gene regulatory networks between the oocyte and the surrounding cumulus cells

Type of signaling

Na pairs (PPIb)

N genes expressed

Ligand

Receptor

Oocyte

CC

Oocyte

CC

Autocrine/Paracrine

964

–

–

131

134

Autocrine

52

–

–

24

–

Autocrine

40

–

–

–

21

Autocrine/Paracrine

5489

2463

2463

93

93

Autocrine/Paracrine

546

268

–

81

81

Autocrine/Paracrine

860

–

397

86

86

Autocrine/Paracrine

1050

778

778

51

–

Autocrine/Paracrine

3762

2790

2790

–

42

Autocrine

146

114

–

35

–

Autocrine

566

–

442

–

31

Paracrine

200

–

156

39

–

Paracrine

336

262

–

–

31

  1. aN number, bPPI protein-protein interaction