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Fig. 5 | BMC Genomics

Fig. 5

From: Identification and analysis of ribosome-associated lncRNAs using ribosome profiling data

Fig. 5

Classification of trans-lncRNAs, ribo-lncRNAs, and noribo-lncRNAs. a The kernel density of the RAI * (1 - spec) scores for human lncRNAs. Two vertical dashed lines represent the 5th percentile (left, upper bound for the reliable ribosome-free lncRNAs, termed “noribo-lncRNAs (green)”) and the 95th percentile (right, lower bound for the reliable ribosome-associated lncRNAs (orange) for further classification) of the RAI * (1 - spec) scores. b The kernel density of the TS scores for human ribosome-associated lncRNAs identified in a. Top 5% of lncRNAs were classified as “trans-lncRNAs (red)” suggesting that stable translation events are likely to occur among them. The remaining lncRNAs were finally classified as “ribo-lncRNA (orange)” indicating that there is an interaction with ribosomes in this part of lncRNAs, but no strong translation activity was observed. c Comparisons among trans-lncRNAs, ribo-lncRNAs, and noribo-lncRNAs for their transcript lengths in human. df show the results for mouse; p-values in c and f were calculated using two-sample t-tests

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