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Table 1 Patient Characteristics: discovery and validation sets for isomiR profiling

From: A Comprehensive Approach to Sequence-oriented IsomiR annotation (CASMIR): demonstration with IsomiR profiling in colorectal neoplasia

  Discovery set Validation set
  Normal Colon Advanced Adenomab CRC Normal Colon Advanced Adenomab CRC
No. of cases 20 26 35 30 20 40
Age
 Mean ± SD 62 ± 5 62 ± 11 59 ± 10 61 ± 13 66 ± 11 70 ± 13
Gender, number (%)
 Female 9 (45) 13 (50) 17 (49) 15 (50) 6 (30) 22 (55)
Location, number (%)       
 Proximala   13 (50) 17 (49)   13 (65) 17 (43)
TNM stage, number (%)
 I    6 (17)    1 (3)
 II    10 (29)    12 (30)
 III    15 (43)    26 (65)
 IV    4 (11)    1 (3)
  1. aProximal lesions include tumors at or proximal to the splenic flexure, and distal lesions are those distal to the splenic flexure
  2. bAdvanced adenoma includes 1) adenoma measuring ≥1 cm in the greatest dimension, with high-grade dysplasia, or with ≥25% villous histologic features, and 2) Sessile serrated adenoma ≥ 1 cm