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Table 1 Patient Characteristics: discovery and validation sets for isomiR profiling

From: A Comprehensive Approach to Sequence-oriented IsomiR annotation (CASMIR): demonstration with IsomiR profiling in colorectal neoplasia

 

Discovery set

Validation set

 

Normal Colon

Advanced Adenomab

CRC

Normal Colon

Advanced Adenomab

CRC

No. of cases

20

26

35

30

20

40

Age

 Mean ± SD

62 ± 5

62 ± 11

59 ± 10

61 ± 13

66 ± 11

70 ± 13

Gender, number (%)

 Female

9 (45)

13 (50)

17 (49)

15 (50)

6 (30)

22 (55)

Location, number (%)

      

 Proximala

 

13 (50)

17 (49)

 

13 (65)

17 (43)

TNM stage, number (%)

 I

  

6 (17)

  

1 (3)

 II

  

10 (29)

  

12 (30)

 III

  

15 (43)

  

26 (65)

 IV

  

4 (11)

  

1 (3)

  1. aProximal lesions include tumors at or proximal to the splenic flexure, and distal lesions are those distal to the splenic flexure
  2. bAdvanced adenoma includes 1) adenoma measuring ≥1 cm in the greatest dimension, with high-grade dysplasia, or with ≥25% villous histologic features, and 2) Sessile serrated adenoma ≥ 1 cm