Table 4 eGenes are often located within the same TAD as their linearly-furthermost, and most-significant, aseQTL/eQTL
QTL type | Cell type | maximum number of eSNPs tested in a chromosome | Sourced TAD set | number of significant eGene in TAD | number of furthermost and most-significant cis-QTL-eGene in the same TAD | Chi-Square test | ||
|---|---|---|---|---|---|---|---|---|
Expected | observed | value | P-value | |||||
aseQTL | white blood | 1,057,269 | hg18:hESC | 13,302 | 1406.379224 | 6375 | 17,553.7238 | 0 |
hg18:IMR90 | 13,790 | 1457.973951 | 7273 | 23,192.8204 | 0 | |||
mm9:mESC | 13,641 | 1442.220643 | 7682 | 26,996.4562 | 0 | |||
mm9:cortex | 13,150 | 1390.308735 | 8670 | 38,116.6453 | 0 | |||
mm10:liver | 12,013 | 1270.09725 | 5101 | 11,554.8757 | 0 | |||
canfam3:liver | 13,046 | 1379.313137 | 6086 | 16,060.8209 | 0 | |||
milk | 1,153,815 | hg18:hESC | 9553 | 1102.23947 | 3862 | 6909.82168 | 0 | |
hg18:IMR90 | 10,019 | 1156.007249 | 4550 | 9964.63198 | 0 | |||
mm9:mESC | 9706 | 1119.892839 | 4764 | 11,857.8462 | 0 | |||
mm9:cortex | 9317 | 1075.009436 | 5608 | 19,114.2541 | 0 | |||
mm10:liver | 8692 | 1002.895998 | 2931 | 3706.85001 | 0 | |||
canfam3:liver | 9638 | 1112.046897 | 3863 | 6805.23726 | 0 | |||
eQTL | white blood | 8964 | hg18:hESC | 327 | 0.2931228 | 114 | 44,108.66 | 0 |
hg18:IMR90 | 340 | 0.304776 | 125 | 51,017.4649 | 0 | |||
mm9:mESC | 322 | 0.2886408 | 125 | 53,883.3149 | 0 | |||
mm9:cortex | 305 | 0.273402 | 123 | 55,090.3719 | 0 | |||
mm10:liver | 284 | 0.2545776 | 91 | 32,346.6467 | 0 | |||
canfam3:liver | 330 | 0.295812 | 119 | 47,633.917 | 0 | |||
milk | 2463 | hg18:hESC | 343 | 0.0844809 | 24 | 6770.19366 | 0 | |
hg18:IMR90 | 348 | 0.0857124 | 25 | 7241.9128 | 0 | |||
mm9:mESC | 356 | 0.0876828 | 34 | 13,115.9732 | 0 | |||
mm9:cortex | 323 | 0.0795549 | 36 | 16,218.7166 | 0 | |||
mm10:liver | 340 | 0.083742 | 23 | 6271.10507 | 0 | |||
canfam3:liver | 362 | 0.0891606 | 22 | 5384.49588 | 0 | |||