| Function in competence | S. pneumoniae | S. mitis | Description | ||||
---|---|---|---|---|---|---|---|---|
ID | Mean fold-change | ID | Mean fold-changec | |||||
TIGR4b | R6d | NCTC12261a | SK321a | NCTC12261 | SK321 | |||
SigX Core Orthologues [29] | DNA uptake and recombination | 0023 | 10 | 0021 | 0342 | 1.4 | 2.3 | DNA repair protein RadA; radA |
0978 | 16 | 1411 | 01508af | 58.6 | 139.6 | Competence protein; coiA | ||
1266 | 64 | 1607 | 0695 | 63.8 | 339.3 | DNA protecting protein DprA; dprA | ||
1908 | 64 | 0826 | 1193 | 98.6 | 697.9 | Single-strand binding protein family; ssbB | ||
1940 | 16 | 0916 | 1658 | 5.3 | 18.8 | Protein RecA; recA | ||
2208 | 128 | 0765 | 1614 | 113.2 | 591.7 | Competence protein ComFA; comFA | ||
2207 | 64 | 01089f | 00402f | 133.6 | 1167.9 | Competence protein, putative; comFC | ||
1808 | 16 | 0438 | 1050 | 57.0 | 694.6 | Type 4 prepilin peptidase; cilC, pilD | ||
0954 | 32 | 1388 | 0421 | 122.8 | 627.9 | ComE operon protein 1; comEA | ||
0955 | 64 | 1389 | 0422 | 93.6 | 839.4 | DNA internalization-related competence protein ComEC | ||
2047 | 64 | 0629 | 1267 | 78.3 | 218.4 | Methyltransferase small domain superfamily | ||
2048 | 64 | 0630 | 1268 | 187.6 | 992.0 | ComG operon protein 6 | ||
2049 | 64 | 01214f | 1269 | 141.4 | 1016.1 | Hypothetical protein; cglE | ||
2050 | 64 | 0631 | 1270 | 164.6 | 852.6 | Competence protein | ||
2051 | 64 | 0632 | 1271 | 192.2 | 1027.7 | Competence protein | ||
2052 | 64 | 0633 | 1272 | 162.5 | 1079.0 | Competence protein CglB; comYB | ||
2053 | 64 | 0634 | 1273 | 146.1 | 929.8 | Putative ABC transporter subunit ComYA; comYA | ||
Lysis | 2201 | 64 | 0760 | 1609 | 134.5 | 458.5 | Choline binding protein D; cbpD | |
Unknown functions in competence | 0021 | 10 | 0019 | 0340 | 1.2 | 1.6 | Deoxyuridine 5′-triphosphate nucleotidohydrolase, dut | |
1981 | 8 | 0563 | 1204 | 1.3 | 4.3 | Competence-induced protein Ccs50; ccs50 | ||
1980 | 8 | 01275f | 00562f | 1.5 | 3.9 | CMP-binding factor; yhaM, cbf1 | ||
2206 | 32 | 0764 | 1613 | 2.2 | 4.1 | Ribosome-associated factor Y; yfiA | ||
0979 | 8 | 1412 | 0443 | 1.5 | 3.4 | Oligopeptidase F; pepB | ||
0782 | 8 | 1288 | 0286 | 7.1 | 47.2 | Conserved domain protein; pilC | ||
1088 | 32 | 1568 | 0646 | 167.3 | 297.6 | DNA repair protein RadC; radC | ||
2044 | -e | 0627 | 1265 | 1.6 | 4.5 | Acetate kinase; ackA | ||
1941 | 32 | 0915 | 1657 | 21.7 | 55.3 | Competence/damage-inducible protein CinA; cinA | ||
Non-Core Orthologues | Unknown functions in competence | 0024 | 8 | 0022 | 0343 | 1.4 | 2.4 | Carbonic anhydrase |
0025 | 4 | 0023 | 0344 | 1.3 | 2.2 | Membrane protein, putative | ||
0031 | 16 | 00941f | 0345 | 6.7 | 1.2 | Hypothetical protein | ||
0030 | 32 | 0025 | 0346 | 6.6 | 26.1 | Competence-induced protein; Ccs16 | ||
0029 | 4 | 0026 | 0347 | 5.0 | 1.9 | Conserved hypothetical protein | ||
2045 | 8 | 0628 | 1266 | 3.3 | 19.8 | Adenine-specific methyltransferase | ||
2197 | 16 | 0757 | 1606 | 3.7 | 86.4 | ABC transporter substrate-binding protein | ||
2198 | 16 | 0758 | 1607 | 3.0 | 118.7 | ABC transporter, permease protein | ||
2199 | 4 | 0759 | 1608 | 3.7 | 92.9 | Conserved hypothetical protein | ||
1939 | 16 | 0917 | 1659 | 4.4 | 10.8 | DNA-damage-inducible protein | ||
0980 | 6 | 1413 | 0444 | 1.7 | 3.9 | O-methyltransferase family protein | ||
0981 | 4 | 1414 | 0445 | 1.3 | 2.7 | Foldase protein PrsA | ||
1072 | 8 | 1421 | 0451 | 1.4 | 2.7 | DNA primase | ||
1073 | 8 | 1422 | 0452 | 1.3 | 3.1 | RNA polymerase sigma factor RpoD | ||
1074 | 8 | 1423 | 0453 | 1.3 | 3.0 | N-6 Adenine-specific DNA methylase YitW | ||
0201 | 8 | 0853 | 1482 | 3.2 | 13.5 | Competence-induced protein Ccs4; ccs4 |