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Fig. 2 | BMC Genomics

Fig. 2

From: Intracellular signalling pathways and cytoskeletal functions converge on the psoriasis candidate gene CCHCR1 expressed at P-bodies and centrosomes

Fig. 2

Expression profiling of the CCHCR1-HEK293 cell lines highlighted cell adhesion and actin cytoskeleton. a Heatmaps showing gene expression of focal adhesion and regulation of actin cytoskeleton in the CCHCR1 Iso1Non-risk (1 N), Iso1Risk (1R), Iso3Non-risk (3 N), and Iso3Risk (3R) cell lines, and in the vector transfected cells (V), and wild type HEK293 (WT). Color key: red represents upregulated and blue downregulated expression (row Z-score). b The expression of FN1, TLN1, and SYT1 in the CCHCR1-HEK293 cell lines was validated with qPCR, and compared with the gene expression in the wild type cells. Error bars: standard deviation. Here shown normalization with HPRT1

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BMC Genomics

ISSN: 1471-2164

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