Fig. 3
From: Landscape of transcriptional deregulation in lung cancer
Training and prediction of the OC-SVM model. a ROC curves for model evaluation with 10-fold cross validation. The positive sets were curated known TF-target regulatory relationships, whereas the negative sets were artificially synthesized (See Methods). ROC curves for three values of log2 gamma parameter were shown: -11, -8, -5. b Predictions of OC-SVM. Left, distribution of TFs by the number of predicted targets. Right, distribution of genes by the number of TFs predicted to target them