Table 1 Pi regulation of vancomycin and lysozyme resistance. The concentration of the compounds is shown as μg per mL. (Pi = K2HPO4)
DifcoNA | ||||||||
Lys | Van | WT | W1 | W2 | L1 | L2 | L4 | L5 |
– | – | ++++ | ++++ | ++++ | ++++ | ++++ | ++++ | ++++ |
10 | – | ++++ | ++++ | ++++ | ++++ | ++++ | ++ | ++++ |
100 | – | ++++ | ++++ | ++++ | ++ | ++ | + | ++ |
500 | – | ++++ | ++++ | ++++ | + | – | – | + |
– | 50 | ++++ | ++++ | ++++ | ++++ | ++++ | ++++ | ++++ |
10 | 50 | ++++ | ++++ | ++++ | ++ | + | – | ++ |
100 | 50 | ++ | ++ | ++ | + | – | – | + |
500 | 50 | ++ | ++ | ++ | – | – | – | – |
DifcoNA + 1%Pi | ||||||||
Lys | Van | WT | W1 | W2 | L1 | L2 | L4 | L5 |
– | – | ++++ | ++++ | ++++ | ++++ | ++++ | ++++ | ++++ |
10 | – | ++++ | ++++ | ++++ | ++ | – | – | ++ |
100 | – | – | – | – | – | – | – | – |
500 | – | – | – | – | – | – | – | – |
– | 50 | – | – | – | ++++ | ++++ | ++++ | ++++ |
10 | 50 | – | – | – | – | – | – | – |
100 | 50 | – | – | – | – | – | – | – |
500 | 50 | – | – | – | – | – | – | – |