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Fig. 5 | BMC Genomics

Fig. 5

From: Transposable elements generate regulatory novelty in a tissue-specific fashion

Fig. 5

Tissue-specific TEs are enriched for TF binding sites, are mostly intronic, and affect gene expression. (a) Motifs enriched in the regions overlapping X7C and and Charlie15a TEs in the breast. (b) Boxplot comparing mean expression for the genes associated to X7C and and Charlie15a in the breast vs all the other tissues. (c) Genomic distribution of the regions overlapping X7C and and Charlie15a TEs in the breast. (d) Motifs enriched in the regions overlapping LTR13_ TEs in pancreas and LCL cells. (e) Boxplot comparing mean expression for the genes associated to LTR13_ in the LCLs vs all the other tissues. (f) Genomic distribution of the regions overlapping LTR13_ in the LCLs. (g) Motifs enriched in the regions overlapping SVAs in the adipose nuclei. (h) Boxplot comparing mean expression for the genes associated to SVAs in the adipose nuclei vs all the other tissues. (i) Genomic distribution of the regions overlapping SVAs in the adipose nuclei. (j) Motifs enriched in the regions overlapping SVAs in the liver. (k) Boxplot comparing mean expression for the genes associated to SVAs in the liver vs all the other tissues. (l) Genomic distribution of the regions overlapping SVAs in the liver

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