Table 3 DR pathways modulated in B57 or A22 genetic background
Induced in B57 | Induced in A22 | ||
|---|---|---|---|
1692 RT sequences / 1082 DR genes | 2425 RT sequences / 1399 DR genes | ||
KEGG pathway | pvalue | KEGG pathway | pvalue |
Lysosome | 0.01 | Focal adhesion | 0.00003 |
Ether lipid metabolism | 0.01 | Regulation of actin cytoskeleton | 0.00004 |
Phosphatidylinositol signaling system | 0.01 | ECM-receptor interaction | 0.0001 |
Inositol phosphate metabolism | 0.01 | p53 signaling pathway | 0.0007 |
Porphyrin and chlorophyll metabolism | 0.03 | Tight junction | 0.0027 |
Notch signaling pathway | 0.04 | MAPK signaling pathway | 0.01 |
Glycerophospholipid metabolism | 0.04 | Steroid biosynthesis | 0.02 |
Adherens junction | 0.05 | Vascular smooth muscle contraction | 0.02 |
Jak-STAT signaling pathway | 0.08 | Wnt signaling pathway | 0.02 |
TGF-beta signaling pathway | 0.09 | Folate biosynthesis | 0.04 |