Fig. 4

Circos plot of eQTL hotspot regions that harbored the transcription factors (TF) EGR4 (rs110242967), RUNX1T1 (rs134095631) and USF1 (rs135914685). Colored boxes represent each chromosome while the colored lines show the association between the regions that harbor the TFs and the genes that were associated with these hotspot regions. USF1 region connections are shown in blue: EGR4 region connections are shown in red: RUNX1T1 region connections are shown in green