Fig. 2

Manhattan plots of significant cis splicing quantitative trait loci (sQTLs, approximate FDR < 0.01 and within 1 Mb of the exon) in white blood cells (a), milk cells (b), liver tissue (c) and muscle tissue (d). A significant sQTLs was defined as a SNP associated with the variation in the exon inclusion ratio and also variation in at least one excision of an adjacent intron at the same significance level. The input SNPs had significance p < 0.0001. sQTLs in all tissues with their associated genes and significance are given in Additional file 8: Table S6