Fig. 8From: Whole-transcriptome changes in gene expression accompany aging of sensory neurons in Aplysia californicaAlterations in CREB signaling. Many genes in the CREB signaling pathway showed altered expression with age, including PKA, an important second messenger in neurons necessary for activation of both CREB and iGluR. See Figure 5 for specific iGluR genes that were downregulatedBack to article page