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Table 8 Results of 5-fold cross validation of our SVM and Barman’s SVM [14] with Barman’s dataset of 1035 positive and 1035 negative PPIs

From: A generalized approach to predicting protein-protein interactions between virus and host

 

SN(%)

SP(%)

ACC(%)

PPV(%)

NPV(%)

MCC

AUC

F1(%)

Our SVM

76.14

83.77

79.95

82.46

77.80

0.601

0.858

79.17

Barman’s SVM

67.00

74.00

71.00

72.00

0.440

0.730

69.41

  1. SN: sensitivity, SP: specificity, ACC: accuracy, PPV: positive predictive value, NPV: negative predictive value, MCC: Matthews correlation coefficient, AUC: the area under the ROC, F1 = 2x(SNxPPV)/(SN+PPV), “–”: not available