Biological Process
|
Number of Enriched Gene Sets Related to the Process
|
Direction
|
---|
Protein synthesis and localization
|
21
|
⬇
|
Transmembrane transport
|
10
|
⬇
|
Nucleocytoplasmic transport
|
7
|
⬇
|
Cell growth
|
6
|
⬆⬇
|
Others
|
4
|
⬆⬇
|
Chromatin maintenance
|
3
|
⬇
|
Dendrite and synapse development
|
3
|
⬆
|
Oxidoreductase activity
|
2
|
⬇
|
- This table summarizes the biological processes significantly altered in the frontal cortex (FC) of Dark Agouti (DA) rats after a single-dose 3,4-methylenedioxymethamphetamine (MDMA) treatment (15 mg/kg, intraperitoneal) 3 weeks earlier. The processes were created based on the network analysis of gene set enrichment x analysis and individual considerations. All significantly enriched GO terms are included in one of the processes. Downward arrows represent down-, upward arrows represent upregulations. In some of the biological processes both up- and downregulated gene sets were present (mixed up- and downward arrows). See text for further details