Fig. 3

Evolutionary relationships for the E proteins of the ZIKV and DENV types. a A neighbor-joining tree likelihood of distance between the minInDel patterns in the E proteins of ZIKV and DENV types. b A topology of the maximum likelihood tree based on a gapless multiple sequence alignment of the E protein sequences of the ZIKV and DENV strains. c A topology of a minimum evolution tree with a distance correction by calculating the minInDel frequencies in the E protein sequences. Virus types and hosts are differentiated by different colours of triangles and circles shown at the front and end of each strain code, and four cases of microcephaly are indicated by asterisks