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Fig. 7 | BMC Genomics

Fig. 7

From: Murine host response to Neisseria gonorrhoeae upper genital tract infection reveals a common transcriptional signature, plus distinct inflammatory responses that vary between reproductive cycle phases

Fig. 7

Principal Component Analysis (PCA) before and after batch correction. All samples are plotted with respect to the first and second Principal Components (PC), computed using log2 (expression) values z-normalized across all samples (to a mean of zero and a standard deviation of one). PCA was performed both prior to (a) and following (b) correction for array batch effect using ComBat. Light and dark colors indicate estrus-phase and diestrus-phase samples, respectively, and gray and green indicate PBS-treated and GC-infected samples, respectively. Samples from array batches 1 and 2 are plotted as circles and squares, respectively. N = 4 for all groups except PBS Estrus N = 3

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BMC Genomics

ISSN: 1471-2164

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