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Table 6 Gene network analysis of immune expression

From: Transcriptional response of honey bee (Apis mellifera) to differential nutritional status and Nosema infection

Interaction

%

Bioprocess

FDR

# Genes

Co-expression

73.72

Positive regulation of antimicrobial peptide biosynthesis

7.90e-7

5/ 28

Genetic

13.17

Defense response to fungus

8.15e-6

5/ 52

Physical

12.74

External biotic stimulus

1.23e-11

12/ 288

Toll signaling pathway

1.30e-9

7/ 47

  1. Immune and defense genes differentially expressed in infected bees fed carbohydrates instead of pollen (PN vs. CN) was analyzed in GeneMania. Types of interactions in the resulting network are described with their percentage. Enriched defense processes were uncovered, of which a select number are described. Gene accounts and FDR were calculated based on the Drosophila genome