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Table 4 Putative causal genes for identified QTL affecting resistance to clinical mastitis

From: Prioritizing candidate genes post-GWAS using multiple sources of data for mastitis resistance in dairy cattle

QTL

Gene

Source*

3: 91961838~ 93,178,041

FAM151A

Gene analysis and RNA-seq

4: 57757451~ 58,741,047

IMMP2L

Gene analysis and MP

5: 105444242~ 106,622,012

FGF6 and/or CCND2

Gene analysis and KEGG / Gene analysis, KEGG and nearest gene

6: 23219637~ 23,719,758

NFKB1

Gene analysis, KEGG, GO, MP and RNA-seq

6: 88479895~ 88,980,376

GC

Gene analysis and MP

6: 92131530~ 93,382,644

NAAA and/or SHROOM3

RNA-seq and gene analysis / RNA-seq and gene analysis

11: 88150188~ 88,993,125

ID2

Gene analysis and MP

13: 61295534~ 62,267,717

CCM2L and/or HCK

Gene analysis, GO, MP and RNA-seq / Gene analysis, GO, MP and RNA-seq

16: 47048599~ 48,086,099

HES2 and/or ACOT7 and/or KCNAB2

Gene analysis and RNA-seq / Gene analysis, nearest gene and RNA-seq / Gene analysis and RNA-seq

19: 42148461~ 43,288,858

KRT32 and/or DHX58 and/or KCNH4 and/or STAT5A and/or STAT3

Gene analysis and RNA-seq / Gene analysis, GO, MP and RNA-seq / Gene analysis, MP and RNA-seq / Gene analysis, nearest gene, KEGG, GO and MP / Gene analysis, KEGG, MP and RNA-seq

20: 38221493~ 38,721,830

CAPSL and/or SPEF2

Gene analysis and RNA-seq / Gene analysis nearest gene and GO

25: 35104498~ 35,604,430

ORAI2 / CUX1

Gene analysis, MP and RNA-seq / Gene analysis, nearest gene and MP

  1. Note, * we used ‘/’ to separate the evidence for different genes, MP stands for mammalian phenotype database