Fig. 2

Lineage specific gene losses evaluated from comparisons between the draft genome of the striped catfish and the available genome of the channel catfish, Icatlurus punctatus. a The catfish lineage lost a gene cluster for sunscreen biosynthesis. The vertebrate sunscreen compound, gadusol, and biosynthetic pathway demonstrated using recombinant zebrafish proteins, EEVS and MT-Ox [39], are shown. b Genomic organization of EEVS and MT-Ox-containing region in vertebrates suggests that the catfish P. hypophthalmus lost both EEVS and MT-Ox genes, but arrangements of neighboring genes are conserved. FRMD4B, FERM domain-containing protein 4B. MitF, microphthalmia-associated transcription factor. MDFIC, MyoD-family inhibitor domain-containing protein-like. FoxP1, Forkhead-related transcription factor 1. c Comparisons of genomic regions between MiTF and MDFIC

zPicture [103] alignments of P. hypophathalmus vs I. punctatus, P. hypophathalmus vs D. rerio and G. gallus vs D. rerio, respectively. d Syntenic regions of catfishes and zebrafish include a pseudogene from a vitamin D-binding protein coding gene in channel catfish. e Syntenic regions containing prikle2a and rhodopsin show the difference between these two catfish genomes. The cPLA2γ gene was not found in the channel catfish genome, but was encoded in another region in zebrafish.