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Table 1 Enrichment analysis showing 20 most overrepresented1 Biological Process for differentially expressed genes2 for the effects of diet and sex in the muscle tissue

From: Impact of energy restriction during late gestation on the muscle and blood transcriptome of beef calves after preconditioning

Biological Process

# genes

FE

P-value

Diet

 Positive regulation of actin cytoskeleton reorganization (GO:2000251)

2

21.68

4.88E-03

 Peptidyl-proline hydroxylation (GO:0019511)

2

21.68

4.88E-03

 Positive regulation of blood vessel endothelial cell migration (GO:0043536)

3

13.21

1.90E-03

 Negative regulation of myeloid cell differentiation (GO:0045638)

4

9.56

1.02E-03

 Membrane depolarization (GO:0051899)

3

9.4

4.70E-03

 Regulation of protein targeting (GO:1903533)

4

6.33

4.26E-03

 Negative regulation of hemopoiesis (GO:1903707)

4

5.75

5.90E-03

 Regulation of cell morphogenesis involved in differentiation (GO:0010769)

6

4.55

2.44E-03

 Regulation of mitochondrion organization (GO:0010821)

5

4.49

5.87E-03

 Regulation of neuron projection development (GO:0010975)

8

4.27

7.09E-04

 Regulation of intracellular transport (GO:0032386)

7

3.55

4.16E-03

 Regulation of cell morphogenesis (GO:0022604)

8

3.33

3.28E-03

 Regulation of neuron differentiation (GO:0045664)

9

3.32

1.86E-03

 Positive regulation of transport (GO:0051050)

14

2.92

3.81E-04

 Regulation of plasma membrane bounded cell projection organization (GO:0120035)

8

2.86

7.79E-03

 Regulation of neurogenesis (GO:0050767)

9

2.68

7.28E-03

 Regulation of nervous system development (GO:0051960)

10

2.55

6.61E-03

 Regulation of transport (GO:0051049)

20

2.08

2.13E-03

 Cell surface receptor signaling pathway (GO:0007166)

20

1.87

6.52E-03

 Regulation of localization (GO:0032879)

25

1.74

7.58E-03

Sex

   

 Histone H3-K27 demethylation (GO:0071557)

2

55.66

1.04E-03

 Kinetochore assembly (GO:0051382)

3

52.18

5.64E-05

 Positive regulation of sodium ion transmembrane transporter activity (GO:2000651)

2

39.76

1.76E-03

 Kinetochore organization (GO:0051383)

3

34.79

1.52E-04

 Positive regulation of glycoprotein biosynthetic process (GO:0010560)

3

34.79

1.52E-04

 Regulation of skeletal muscle contraction (GO:0014819)

2

34.79

2.19E-03

 Positive regulation of glycoprotein metabolic process (GO:1903020)

3

29.82

2.25E-04

 Centromere complex assembly (GO:0034508)

3

21.97

4.97E-04

 Establishment of melanosome localization (GO:0032401)

3

20.87

5.68E-04

 Establishment of pigment granule localization (GO:0051905)

3

19.88

6.46E-04

 Melanosome localization (GO:0032400)

3

19.88

6.46E-04

 Pigment granule localization (GO:0051875)

3

18.98

7.30E-04

 ATP hydrolysis coupled transmembrane transport (GO:0090662)

3

16.06

1.14E-03

 ATP hydrolysis coupled proton transport (GO:0015991)

3

16.06

1.14E-03

 Energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988)

3

14.91

1.38E-03

 Regulation of glucose metabolic process (GO:0010906)

5

9.53

2.41E-04

 Regulation of cellular carbohydrate metabolic process (GO:0010675)

5

7.65

6.29E-04

 Regulation of carbohydrate metabolic process (GO:0006109)

5

6.5

1.26E-03

 Chromosome organization (GO:0051276)

17

2.59

3.56E-04

 Cellular macromolecular complex assembly (GO:0034622)

14

2.57

1.32E-03

  1. 1P-value < 0.05;
  2. 2q-value < 0.05;
  3. FE = fold enrichment