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Table 4 10 most differentially Expressed Genes1 in the blood for biologically relevant contrasts

From: Impact of energy restriction during late gestation on the muscle and blood transcriptome of beef calves after preconditioning

Gene symbol

Gene name

Biological function

q-value

DEG for effect of interaction diet-by-weaning

 USF3

Upstream transcription factor family member 3

Regulates Major Histocompatibility Complex [82]

1.13E-04

 STARD6

StAR related lipid transfer domain containing 6

Structure and lipid transport mechanism [83]

3.10E-04

 PHC3

Polyhomeotic homolog 3

 

3.17E-04

 BRMS1L

Breast cancer metastasis-suppressor 1 like

Metastasis suppression [84]

4.87E-04

 MPV17L

MPV17L mitochondrial inner membrane protein like

Up- or down-regulation of the genes of antioxidant enzymes [85]

4.92E-04

 NBEAL1

Neurobeachin like 1

Vesicle trafficking, membrane dynamics and receptor signaling [86]

7.31E-04

 C5H12orf4

Chromosome 5 open reading frame, human C12orf4

 

7.59E-04

 INO80D

INO80 complex subunit D

DNA damage responses [51]

8.00E-04

 TIGD3

Tigger transposable element derived 3

 

8.94E-04

 KLRK1

Killer cell lectin like receptor F1

Stimulates natural killer (NK) cells cytoxicity and cytokine release [50]

9.05E-04

DEG for effect of interaction diet-by-vaccination

 LOC104968634

Antimicrobial peptide NK-lysin-like

Antimicrobial activity [87]

6.62E-04

 GPR161

G protein-coupled receptor 161

Involved in neural tube development [88]

2.13E-03

 KLRF1

Killer cell lectin like receptor F1

Stimulates NK cells cytoxicity and cytokine release [50]

2.20E-03

 PMCH

Pro-melanin concentrating hormone

Feed intake control [89]

2.81E-03

 PIK3C2G

Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma

Control cell proliferation [90]

3.15E-03

 KRT24

Keratin 24

 

3.64E-03

 PRRT3

Proline rich transmembrane protein 3

Protein binding [91]

3.74E-03

 QRICH2

Glutamine rich 2

Cupper regulation [92]

4.18E-03

 HIST2H2AB

Histone cluster 2 H2A family member B

Play a central role in transcription regulation, DNA repair and DNA replication [93]

4.22E-03

 OASL

2′-5′-oligoadenylate synthetase like

Response to viral infections [52]

4.73E-03

  1. 1P-value < 0.05 for significant (q-value < 0.05) effects of diet-time interaction;
  2. Biological Function, based on cited reference