Fig. 6

Examples of complementarity between miRNAs seed sequences and the secondary structure of their putative targets. Using mfold [25] to predict and draw secondary structures of 3’UTR of the predicted targets, we could show that miR-34 and miR-190 map to loops rather than stems in the secondary structures of their targets, takeout (GSSPFG00021718001-RA) in (a) and acyl-CoA desaturase (GSSPFG00006314001-RA) in (b), their most differentially expressed candidates, respectively