Fig. 7

Fixed-cut at h=1.3 versus F1 strategy in CLEANsmall. The red rectangle on top of the dendrogram on the left highlights an example cluster obtained from the fixed-cut approach at a height of 1.3 (blue line). The F1 strategy (on the right) detected five smaller clusters from the same branch that come from various levels of tree height and cannot be detected together using one single cut. All these clusters are defined by a unique GO term which indicates a functional difference between these gene groups. For example, cluster 1178 is enriched in the T-cell receptor signaling pathway, whereas cluster 967 is enriched in the B-cell receptor signaling pathway